I have a truck avenger on my 4x4, which has a 350 with a roller cam designed for high torque. I had (and still have) problems with mixture which I have never had with any other Holley. I could make it idle fine, but mid throttle acceleration was way rich. Cruising and full throttle weren't quite right either, and this was right out of the box. After what seemed like a million combinations, I gave up and put 3 sizes smaller primaries and 7 (yes seven) sizes smaller secondaries in. The secondaries are a little too lean, but I'm sick of messing with it. The signal from the cam profile really seems to screw it up. It seems to me that the power valve comes in at a really low #, something like 2.5. I'm looking at putting some sort of FI on.
Mine is a 670 cfm.