I'm in the process of finishing up my 30X44' building with 12' ceilings and an upstairs (attic/bonus room trusses). It is a poured foundation w/ 2X6 walls, fully insulated... I had a contractor build it to the point where the exerior was complete, but unpainted (cement board siding). I did all of the wiring, plumbing, heating, interior paint (still finishing) and trim work.
Cost will depend on a lot of things. For my building, I probably could have been in a range anywhere as low as $25K up to $75K. I can tell you that I will end up closer to the top end of that range due to the fact that it was all stick-framed and made to match my house A pole building will be less expensive.
I did some research on metal buildings when we were looking to build on some property that we owned and came to the conclusion that unless you are spanning 50'+ with the trusses it wasn't much of a cost advantage to go metal.
Disclaimer - - I'm not a builder or construction expert, so others may be able to offer more detailed better info.
Here is a pic of my shop.